The city attracts numerous immigrants from all over Brazil and even from foreign countries, due to the vibrant economy and for being the hub of most Brazilian companies.
The region of modern-day São Paulo, then known as Piratininga plains around the Tietê River, was inhabited by the Tupi people, such as the Tupiniquim, Guaianas, and Guarani.
The city has cultural, economic and political influence both nationally and internationally.
It is home to monuments, parks and museums such as the Latin American Memorial, the Ibirapuera Park, Museum of Ipiranga, São Paulo Museum of Art, and the Museum of the Portuguese Language.
The municipality is also the Earth's 11th largest city proper by population.
Mem de Sá forbade colonists to use the "Path Piraiquê" (Piaçaguera today), because of frequent Indian raids along it.
It exerts strong international influences in commerce, finance, arts and entertainment.
The name of the city honors the Apostle, Saint Paul of Tarsus.
The site was separated from the coast by the Serra do Mar, called by the Indians Serra Paranapiacaba.
The college was named for a Christian saint and its founding on the feast day of the celebration of the conversion of the Apostle Paul of Tarsus.